IN-VIVO EVALUATION OF 5-HYDROXYTRYPTAMINE STIMULATION OF THE TESTES IN THE FIDDLER-CRAB, UCA-PUGILATOR - A PRESUMED ACTION ON THE NEUROENDOCRINE SYSTEM
R. Sarojini et al., IN-VIVO EVALUATION OF 5-HYDROXYTRYPTAMINE STIMULATION OF THE TESTES IN THE FIDDLER-CRAB, UCA-PUGILATOR - A PRESUMED ACTION ON THE NEUROENDOCRINE SYSTEM, Comparative biochemistry and physiology. C. Comparative pharmacologyand toxicology, 106(2), 1993, pp. 321-325
1. Male fiddler crabs, Uca pugilator, received injections of 5-hydroxy
tryptamine (5-HT, serotonin). The crabs showed dose-dependent testicul
ar development. 2. Like 5-HT, the 5-HT releaser fenfluramine and the 5
-HT potentiator fluoxetine induced testicular maturation also, but the
5-HT receptor blocker LY-53857 did not. 3. The data support the hypot
hesis that 5-HT exerts this stimulatory effect on the testes indirectl
y, by triggering release of gonad-stimulating hormone.