MONOAMINE-OXIDASE ACTIVITY IN HEPATOPANCREAS OF OCTOPUS-VULGARIS

Authors
NICOTRA A SENATORI O SANTANGELO G
Citation
A. Nicotra et al., MONOAMINE-OXIDASE ACTIVITY IN HEPATOPANCREAS OF OCTOPUS-VULGARIS, Comparative biochemistry and physiology. C. Comparative pharmacologyand toxicology, 106(2), 1993, pp. 479-482
Citations number
28
Categorie Soggetti
Biology,"Pharmacology & Pharmacy",Toxicology
Journal title
Comparative biochemistry and physiology. C. Comparative pharmacologyand toxicology → ACNP
ISSN journal
07428413
Volume
106
Issue
2
Year of publication
1993
Pages
479 - 482
Database
ISI
SICI code
0742-8413(1993)106:2<479:MAIHOO>2.0.ZU;2-A
Abstract
1. Monoamine oxidase activity has been studied in hepatopancreas of Oc topus vulgaris using 5-HT and PEA as substrates. 2. Time courses of MA O activity against 5-HT and PEA show that the enzyme has higher affini ty for PEA than for 5-HT. 3. MAO activity against 5-HT appears more se nsitive than MAO activity against PEA, to variations of the temperatur e (range 17-67-degrees-C). 4. The inhibition curves obtained with clor gyline and deprenyl indicate that MAO activity is due to a single form of the enzyme, not corresponding to type A and type B MAO. 5. Semicar bazide 10(-4) M does not affect the deamination of 5-HT and PEA, demon strating that a semicarbazide-sensitive amine oxidase is not involved in this process.