SURVIVAL IN A CASE OF LIFE-THREATENING FLECAINIDE OVERDOSE

Flecainide acetate is a potent class Ic anti-arrhythmic drug with majo r sodium channel blocking actions. On the surface electrocardiogram th is results in QTc interval prolongation. Overdose with class Ic drugs (< 0.1 % of total intoxications) is uncommon, but management: is diffi cult and tl-Ie mortality high [1]. Serious flecainide overdose is char acterised by ventricular tachyarrhythmias, severe bradycardia and vari able degrees of atrioventricular block. This report describes a case o f life-threatening flecainide overdose in a previously fit individual, resulting in a combination of cardiac disturbances. The treatment opt ions and management are discussed.