I. Jarvela et al., THE EFFECTS OF A COPPER-INTRAUTERINE DEVICE ON THE UTERINE ARTERY BLOOD-FLOW IN REGULARLY MENSTRUATING WOMEN, Human reproduction (Oxford. Print), 13(7), 1998, pp. 1841-1845
The aim of the study was to evaluate the effect of a copper-intrauteri
ne device (IUD) on uterine artery blood flow during the midluteal phas
e and on the first day of the menstrual cycle using pulsed colour Dopp
ler ultrasonography, Twenty-one regularly menstruating women (18-45 ye
ars) who were willing to use copper-IUD contraception participated in
the study. The patients were first examined without the IUD in the mid
luteal phase 6-9 days before the expected onset of menstruation and on
the first day of menstruation, after which the IUD was inserted. Thre
e months later the patients were examined again on the corresponding c
ycle days. The patients estimated the level of dysmenorrhoeic pain wit
h a scoring system. Transvaginal ultrasonography with colour flow imag
ing was used to measure the pulsatility index (PI) in the uterine arte
ries. There were no significant changes in the uterine artery blood fl
ow after the insertion of the IUD during menstruation or in the midlut
eal phase. In patients with increased IUD-related pain during menstrua
tion (n = 5), however, there was a decrease in PI (2.87 +/- 0.52 versu
s 2.41 +/- 0,23, P = 0.05) after IUD insertion. The decrease in the me
an PI was present in all five patients. In conclusion, copper-IUD does
not induce any major changes in the resistance of the uterine artery
blood flow, although during menstruation in patients with increased me
nstrual pain after IUD insertion there seems to be a decrease in the u
terine artery PI.