UTERINE LEIOMYOMATA - A FEATURE OF ACROMEGALY

In order to assess the prevalence of leiomyomata in patients diagnosed with acromegaly, files of all women so diagnosed were obtained (n = 2 5). Eight of these patients had undergone hysterectomy. In eight of th e remaining patients, assessment of the uterus was performed by gynaec ological examination and transvaginal ultrasound. The prevalence of le iomyomata was 81% (13/16) in patients who had undergone hysterectomy ( 8/8) or who underwent gynaecological examination (5/8), In conclusion, the very high prevalence of leiomyomata in patients diagnosed with ac romegaly warrants the inclusion of growth hormone excess as a cause of leiomyomata. Leiomyomata are a feature of the organomegalic syndrome associated with acromegaly.