A FACILE SYNTHESIS OF 4(3H)-PTERIDINONE DERIVATIVES BY UTILIZING SUBSTITUTED)CARBAMOYL]-2-PYRAZYL)IMINOPHOSPHORANES

Authors
OKAWA T KAWASE M EGUCHI S
Citation
T. Okawa et al., A FACILE SYNTHESIS OF 4(3H)-PTERIDINONE DERIVATIVES BY UTILIZING SUBSTITUTED)CARBAMOYL]-2-PYRAZYL)IMINOPHOSPHORANES, Synthesis, (8), 1998, pp. 1185-1194
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
8
Year of publication
1998
Pages
1185 - 1194
Database
ISI
SICI code
0039-7881(1998):8<1185:AFSO4D>2.0.ZU;2-Y
Abstract
The intermolecular aza-Wittig reaction of iminophosphoranes 4 derived from 3-aminopyrazine-2- (N-substituted)-carboxamide derivatives 2 with various acyl chlorides followed by heterocyclization provided an effi cient synthetic route to 2,3-disubstituted 4(3H)-pteridinone derivativ es 5.