PATIENT RECALL OF THERAPEUTIC PARALYSIS IN A SURGICAL CRITICAL CARE UNIT

Citation
Bkj. Wagner et al., PATIENT RECALL OF THERAPEUTIC PARALYSIS IN A SURGICAL CRITICAL CARE UNIT, Pharmacotherapy, 18(2), 1998, pp. 358-363
Citations number
29
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
ISSN journal
02770008
Volume
18
Issue
2
Year of publication
1998
Pages
358 - 363
Database
ISI
SICI code
0277-0008(1998)18:2<358:PROTPI>2.0.ZU;2-Y
Abstract
Study Objective. To investigate patient recall of therapeutic paralysi s (TP) in a surgical critical care unit. Design. Prospectively applied structured interview of patients undergoing TP over 18 months. Settin g. Surgical critical care unit with 27 beds at a tertiary care univers ity teaching hospital. Patients. Forty patients admitted for postopera tive care after coronary artery bypass graft surgery, trauma, or gastr ointestinal surgery. Interventions. Patients received TP and concurren t sedation with benzodiazepines, propofol, and narcotics. Measurements and Main Results. After the end of TP patients were asked to recall t he experience, and their responses were ranked on a four-point ordinal scale. Four of 11 patients recalled mostly negative events and experi ences with TP, such as sleeplessness, discomfort, pain, anxiety, and i nconsistent caregiver communication. All patients with recall experien ced fear, anxiety, and sleeplessness. Single-drug therapy with propofo l and inadequate benzodiazepine dosing were linked to patient recall. Conclusions. Patient recollection from TP may be more common than appr eciated and is generally unpleasant. Adequate dosing with benzodiazepi nes and narcotics is warranted to prevent recall and discomfort.