STUDY ON PENICILLIN-G LIQUID - LIQUID EXTRACTION WITH AND WITHOUT CHEMICAL-REACTION

Citation
D. Cascaval et al., STUDY ON PENICILLIN-G LIQUID - LIQUID EXTRACTION WITH AND WITHOUT CHEMICAL-REACTION, Hungarian journal of industrial chemistry, 26(2), 1998, pp. 141-146
Citations number
10
Categorie Soggetti
Engineering, Chemical","Chemistry Applied",Chemistry
ISSN journal
01330276
Volume
26
Issue
2
Year of publication
1998
Pages
141 - 146
Database
ISI
SICI code
0133-0276(1998)26:2<141:SOPL-L>2.0.ZU;2-F
Abstract
Using a modified extraction cell of Lewis type, the limiting steps of the Penicillin G physical extraction with butyl acetate and reactive r eaction with Amberlite LA-2 were established. Two types of calculation of the values of mass transfer coefficients and potential for each ex traction system were used. The established mathematical correlation be tween mass flow and mass transfer coefficient of Penicillin G with Re and SC numbers, or rotation speed, offer a good concordance with exper imental data. Finally, the kinetics of the reactive extraction of Peni cillin G with Amberlite LA - 2 was studied and the specific reaction r ate was determined: k(1) = 5.927.10(-4) dm(3) mol(-1) s(-1). In compar ing with the experimental data, this value offers an average deviation of 4.04 %.