AN UNUSUAL CASE OF CREUTZFELDT-JAKOB-DISEASE

A patient with histopathologically verified sporadic Creutzfeldt-Jakob disease (CJD) presented initially with diplopia, sleep disturbances, and L-dopa-responsive parkinsonism. After more than a year of slow pro gression, he did not become demented, and failed to fulfill the clinic al criteria for possible CJD. No clinical examinations currently propo sed to detect CJD showed the disease. CJD should be in the differentia l diagnosis of ''parkinson plus'' syndromes until a different etiology has been found or a histopathologic examination performed.