A prospective study correlating cytopathology with clinical morphology
and histopathology in 22 patients with lepromatous leprosy was perfor
med. Aspirates were taken from skin lesions in all patients. Lymph nod
e aspirates were also performed in four patients with lymphadenopathy.
Fine-needle aspirates yielded sufficient cellular material with excel
lent preservation of morphological detail. Diagnosis and correlation w
ith bacillary index, clinical and histopathological findings was possi
ble in all patients. In addition, the two patterns, partial and diffus
e, of lymph node involvement could be recognized. Fine-needle aspirati
on cytology is a simple method for the laboratory assessment of lepros
y.