METALATION OF PYRIDINE N-OXIDES AND APPLICATION TO SYNTHESIS

Authors
MONGIN O ROCCA P THOMASDITDUMONT L TRECOURT F MARSAIS F GODARD A QUEGUINER G
Citation
O. Mongin et al., METALATION OF PYRIDINE N-OXIDES AND APPLICATION TO SYNTHESIS, Journal of the Chemical Society. Perkin transactions. I, (19), 1995, pp. 2503-2508
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
19
Year of publication
1995
Pages
2503 - 2508
Database
ISI
SICI code
0300-922X(1995):19<2503:MOPNAA>2.0.ZU;2-Y
Abstract
Regio- and chemi-selective, directed ortho-lithiation of 2-, 2,5- or 3 ,4-substituted pyridine N-oxides has been achieved with diisopropylami de and butyllithium. Polysubstituted pyridine N-oxides, azaxanthone, a nd an isomer of orelline have been synthesized by such methods.