NEGATIVE ASSOCIATION BETWEEN ASTHMA AND VARIANTS OF CC16(CC10) ON CHROMOSOME 11Q13 IN BRITISH AND JAPANESE POPULATIONS

Authors
GAO PS MAO XQ KAWAI M ENOMOTO T SASAKI S TANABE O YOSHIMURA K SHALDON SR DAKE Y KITANO H COULL P SHIRAKAWA T HOPKIN JM
Citation
Ps. Gao et al., NEGATIVE ASSOCIATION BETWEEN ASTHMA AND VARIANTS OF CC16(CC10) ON CHROMOSOME 11Q13 IN BRITISH AND JAPANESE POPULATIONS, Human genetics, 103(1), 1998, pp. 57-59
Citations number
19
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
103
Issue
1
Year of publication
1998
Pages
57 - 59
Database
ISI
SICI code
0340-6717(1998)103:1<57:NABAAV>2.0.ZU;2-E
Abstract
The gene encoding Clara cell-derived inflammatory molecule CC16 has be en cited as a candidate gene for atopic asthma on chromosome 11q13. A genetic association study was performed with variants of the CC16 gene on chromosome 11q13 in relation to asthma in British (n = 275) and Ja panese (n = 300) populations. No significant association was found bet ween asthma and CC16 genotypes, irrespective of atopic status in these two populations. These data suggest that CC16 might not be the major locus for asthma on 11q13.