THIN-FILMS IN BIOSENSORS

Thin films are used in every domain of biosensor systems as for sample handling, biological recognition and amplification, transduction and electronic signal processing. Several planar microelectrochemical chip s with thin-film electrodes of different shapes and arrangements on Si or glass substrates have been developed and utilized in voltammetric and potentiometric sensors. Bilayer lipid membranes (BLMs) are very '' adaptive'' thin-film materials applicable in biosensors. Forming of BL Ms on planar chip with thin-film electrodes has opened up new possibil ities for the development of miniaturized biosensors as well as for ba sic research on electrical and mechanical properties of biological mem branes. (C) 1998 Elsevier Science Ltd. All rights reserved.