The role of empirically supported, manual-based treatments in clinical
practice is controversial. This article attempts to clarify misunders
tandings that may impede their effective use. Manual-based treatments
encourage focal interventions, facilitate training and supervision of
therapists, and expedite clinical audit. They are consistent with an a
ctuarial approach to treatment, which, on average, is likely to prove
superior to subjective clinical judgment. Treatment manuals can provid
e greater flexibility and self-correcting features than is often assum
ed. Comorbidity does not exclude their use. Far from hampering innovat
ion, their use is likely to spur new developments. Manual-based treatm
ents require specific therapeutic skills. Although effective, empirica
lly supported manuals fall short of helping large numbers of patients.
Treatment manuals must become more ''therapist friendly'' by includin
g richer practical details on their use, as well as greater specificat
ion of some of the ''nonspecific'' factors in therapy.