Radiologic examination of the upper gastrointestinal tract, or the upp
er gastrointestinal series, is at a crossroads. As we approach the 21s
t century, it is possible to envision two very different scenarios for
the future of this examination. The gradual but steady decline in the
number of upper gastrointestinal studies done during the past decade
could continue or even accelerate until this technique is no longer us
ed in diagnostic radiology. Or, spurred by new concerns about cost and
safety In a rapidly changing political and economic environment, the
upper gastrointestinal series could undergo a dramatic resurgence, sup
planting endoscopy as the primary diagnostic test in patients with sym
ptoms in the upper gastrointestinal tract. Radiologists may ultimately
have a pivotal role in determining the fate of the upper gastrointest
inal series by their commitment or lack of commitment to perpetuating
this form of examination. In this article, we consider the status of t
he upper gastrointestinal series in current medical practice and the c
hallenges we face if it is to remain a useful diagnostic technique in
the 21st century.