Psychosis is one of many possible psychiatric disturbances associated
with endocrinologic abnormalities. Previous reports linking psychosis
with hypopituitarism have been limited. Furthermore, such reports sugg
ested that the psychotic symptoms were more accurately part of a delir
ium. We report two patients with hypopituitarism who presented with ps
ychotic symptoms, in the absence of an altered sensorium. They were as
signed functional psychiatric diagnoses on initial presentation. Their
symptoms abated after correction of underlying hormonal abnormalities
. The evaluation and treatment of psychiatric disturbances associated
with hypopituitarism are discussed. (C) 1998 Elsevier Science Inc.