Study Design. An imaging study was designed to evaluate disc degenerat
ion and segmental instability in the cervical spine. Objectives. To co
mpare the magnetic resonance imaging assessment of disc degeneration w
ith the conventional plain radiographic evaluation of cervical segment
al instability. Summary of Background Data. No studies have been condu
cted to investigate the association of disc degeneration with cervical
instability. Methods. Two hundred sixty consecutive patients with sus
pected cervical spine disorders were analyzed for horizontal and angul
ar displacements on lateral flexion and extension radiographs and disc
degeneration on T2-weighted magnetic resonance images of the cervical
vertebrae. Results. In all intervertebral levels, the grade of disc d
egeneration increased significantly (P < 0.01) with age. Cervical inst
ability was identified in 151 segments (14.5%) and correlated with Gra
de 1 and Grade 2 degeneration in the intervertebral discs (P < 0.01).
Conclusions. Cervical segmental instability may indicate early degener
ation of intervertebral disc in the cervical vertebrae.