EFFECT OF DIRECT THROMBIN INHIBITION WITH BIVALIRUDIN (HIRULOG) ON RESTENOSIS AFTER CORONARY ANGIOPLASTY

Authors
BURCHENAL JEB MARKS DS MANN JT SCHWEIGER MJ ROTHMAN MT GANZ P ADELMAN B BITTL JA
Citation
Jeb. Burchenal et al., EFFECT OF DIRECT THROMBIN INHIBITION WITH BIVALIRUDIN (HIRULOG) ON RESTENOSIS AFTER CORONARY ANGIOPLASTY, The American journal of cardiology, 82(4), 1998, pp. 511
Citations number
19
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
82
Issue
4
Year of publication
1998
Database
ISI
SICI code
0002-9149(1998)82:4<511:EODTIW>2.0.ZU;2-H
Abstract
The direct antithrombin, bivalirudin, did not reduce angiographic rest enosis measured either as the dichotomous restenosis rate of 62% for b ivalirudin and 58% for heparin (p = 0.70), or as the late loss in lume n diameter of 0.44 +/- 0.47 mm for bivalirudin and 0.39 +/- 0.53 mm fo r heparin (p = 0.62). Direct thrombin inhibition with bivalirudin neit her reduces angiographic restenosis nor alters the impact of several e stablished risk factors for restenosis.