USEFULNESS OF TACROLIMUS VERSUS CYCLOSPORINE AFTER PEDIATRIC HEART-TRANSPLANTATION

Authors
HERZBERG GZ ROSSI AF COURTNEY M LANSMAN SL GELB BD PARNESS IA LAI WW
Citation
Gz. Herzberg et al., USEFULNESS OF TACROLIMUS VERSUS CYCLOSPORINE AFTER PEDIATRIC HEART-TRANSPLANTATION, The American journal of cardiology, 82(4), 1998, pp. 541
Citations number
10
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
82
Issue
4
Year of publication
1998
Database
ISI
SICI code
0002-9149(1998)82:4<541:UOTVCA>2.0.ZU;2-5
Abstract
This study compared the early clinical course of 9 pediatric heart tra nsplantation recipients treated with cyclosporine A-based immunosuppre ssion with 10 similarly aged recipients treated with tacrolimus-based therapy. One-year follow-up after transplantation revealed that tacrol imus-treated children had similar left ventricular function, experienc ed fewer episodes of severe rejection, were more rapidly weaned from c orticosteroids, and had relatively few side effects from immunosuppres sion compared with cyclosporine A-treated children.