STRUCTURE OF BIS(2-AMINO-5-BENZOYLPHENYL) DISELENIDE

The title compound, 3,3'-diselenobis(4-amino-benzophenone), is one of a series of antioxidant drugs, which has glutathione peroxidase activi ty. This diselenide can be generated in vivo by administration of the corresponding benzoselenazolinone as a pro-drug. It is important to co rrelate the structure with the pharmacological parameters. In an initi al approach the structure of this compound was determined by X-ray ana lysis; this, in turn, dictates the structure of the corresponding benz oyl benzoselenazolinone.