4-(6-CHLORO-3-(4-CHLOROBENZYL)IMIDAZO[4,5 -D]PYRIDIN-2-YL)-3,3-DIMETHYLBUTANOIC ACID

Authors
RODIER N CEOLIN R AGAFONOV V TOSCANI S DUGUE J NICOLAI E TEULON JM
Citation
N. Rodier et al., 4-(6-CHLORO-3-(4-CHLOROBENZYL)IMIDAZO[4,5 -D]PYRIDIN-2-YL)-3,3-DIMETHYLBUTANOIC ACID, Acta crystallographica. Section C, Crystal structure communications, 49, 1993, pp. 2034-2037
Citations number
5
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
49
Year of publication
1993
Part
11
Pages
2034 - 2037
Database
ISI
SICI code
0108-2701(1993)49:<2034:4->2.0.ZU;2-9
Abstract
The two independent molecules in the asymmetric unit of )imidazoI[4,5- b]pyridin-2-yl)-3,3-dimethylbutanoic acid have similar geometries exce pt for their dimethylbutanoic acid groups. The imidazopyridine group a nd the phenyl ring least-square planes make a dihedral angle of 102.34 (9)degrees in molecule (1) and 117.04(8)degrees in molecule (2). The c arboxylic group of (2) occupies two positions with equal occupancy fac tors. The C(17)-C(18) bond (C-beta-C<(gamma>)) of the butanoic acid ch ain is slightly longer than usual as a result of steric hindrance. Two O-H...N hydrogen bonds take part in the cohesion of the structure.