6-(2-METHYLPROPYLTHIO)-2-PYRIDYL METHANESULFONATE

Authors
MACKAY MF HOLAN G WERNERT GT WINKLER DA
Citation
Mf. Mackay et al., 6-(2-METHYLPROPYLTHIO)-2-PYRIDYL METHANESULFONATE, Acta crystallographica. Section C, Crystal structure communications, 49, 1993, pp. 2039-2040
Citations number
6
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
49
Year of publication
1993
Part
11
Pages
2039 - 2040
Database
ISI
SICI code
0108-2701(1993)49:<2039:6M>2.0.ZU;2-7
Abstract
The title compound, C10H15NO3S2, is an acetylcholinesterase inhibitor when bioactivated to the sulfoxide or sulfone. The pyridine ring atoms are coplanar to within experimental error and the 2-methylpropylthio substituent is extended with atoms C6, S6, C8 and C9 lying close to th e ring plane [torsion angle 177.0(4)degrees]. The orientation of the m ethanesulfonate moiety to the pyridine ring is given by the torsion an gle C2-O2-S2-C7=84.4(4)degrees.