We study a general nonlinear ODE system with fast and slow variables,
i.e., some of the derivatives are multiplied by a small parameter. The
system depends on an additional bifurcation parameter. We derive a no
rmal form for this system, valid close to equilibria where certain con
ditions on the derivatives hold. The most important condition concerns
the presence of eigenvalues with singular imaginary parts, by which w
e mean that their imaginary part grows without bound as the small para
meter tends to zero. We give a simple criterion to test for the possib
le presence of equilibria satisfying this condition. Using a center ma
nifold reduction, we show the existence of Hopf bifurcation points, or
iginating from the interaction of fast and slow variables, and we dete
rmine their nature. We apply the theory, developed here, to two exampl
es: an extended Bonhoeffer-van der Pol system and a predator-prey mode
l. Our theory is in good agreement with the numerical continuation exp
eriments we carried out for the examples.