Purpose: Endopyelotomy has been proposed as a technique to treat urete
ropelvic junction obstruction after failed open pyeloplasty. However,
to our knowledge no long-term results of this treatment have been repo
rted. We report the long-term followup of a cohort of patients in whom
pyeloplasty failed and who subsequently were treated with endopyeloto
my. Materials and Methods: From January 1985 to February 1996, 72 pati
ents in whom open surgical pyeloplasty failed were treated with percut
aneous endopyelotomy. Mean patient age was 35 years (range 5 to 82). T
he interval between pyeloplasty and subsequent failure ranged from 2 m
onths to 30 years (mean 57 months). The major presenting symptoms were
pain in 82% of cases, fever and urinary tract infections in 37.5%, st
one formation in 25% and gross hematuria in 21%. Results: Antegrade en
dopyelotomy using a hooked knife was performed in all patients with no
unusual difficulty and minimal complications. A total of 63 patients
(87.5%) had long lasting clinical and radiographic treatment success a
fter a mean followup of 88.5 months. Of the 9 endopyelotomy failures (
12.5%) 7 (77.8%) were detected immediately after stent removal at 6 we
eks, 1 (11.1%) at 6 months and 1 (11.1%) at 10 months postoperatively
(mean failure inter-val 3.3 months). The failures were corrected with
repeat endopyelotomy in 1 patient, pyeloplasty in 3, ileal interpositi
on in 1 and nephrectomy in 4. Conclusions: Endopyelotomy is the treatm
ent of choice for recurrent ureteropelvic junction obstruction after f
ailed pyeloplasty, with a high and sustained long-term success rate an
d no reported new failures after 1-year followup. Furthermore, endopye
lotomy is technically easier with less morbidity than repeat open pyel
oplasty.