A. Jonczyk et U. Lorencewiczpakulska, CONDENSATION OF 2-BENZOYL-1-CYANO-1,2-DIHYDROISOQUINOLINE WITH ELECTROPHILIC ALKENES UNDER PHASE-TRANSFER CATALYTIC (PTC) CONDITIONS, Journal of chemical research. Synopses (Print), (6), 1998, pp. 350
Condensation of Reissert compound 1 with electrophilic alkenes 2 carri
ed out in the presence of 50% aqueous sodium hydroxide and benzyltriet
hylammonium chloride (TEBAC) as a catalyst, affords 1-(2-substituted-e
thyl) isoquinolines 3 and/or 4.