IN-VITRO CHARACTERIZATION OF POLY(ETHYLENE) GLYCOL CALCIUM CITRATE MICROSPHERES AS A DELIVERY SYSTEM FOR THE STUDY OF REPARATIVE DENTINOGENESIS

Citation
Ar. Hunter et al., IN-VITRO CHARACTERIZATION OF POLY(ETHYLENE) GLYCOL CALCIUM CITRATE MICROSPHERES AS A DELIVERY SYSTEM FOR THE STUDY OF REPARATIVE DENTINOGENESIS, Endodontics & dental traumatology, 14(4), 1998, pp. 159-162
Citations number
4
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
ISSN journal
01092502
Volume
14
Issue
4
Year of publication
1998
Pages
159 - 162
Database
ISI
SICI code
0109-2502(1998)14:4<159:ICOPGC>2.0.ZU;2-G
Abstract
The characterization of poly(ethylene) glycol calcium citrate microsph eres is described. The calcium content and content uniformity of micro spheres, prepared at five concentrations ranging from 46.56 mu g/g to 81.49 mg/g, were determined by spectroscopy. Under sink conditions fir st-order in vitro dissolution kinetics were observed. Granules contain ing approximately SO mg Ca++/g PEG gave an in vitro calcium release ov er a 3-day period similar to that of a calcium hydroxide product, Pulp dent(R).