Ar. Hunter et al., IN-VITRO CHARACTERIZATION OF POLY(ETHYLENE) GLYCOL CALCIUM CITRATE MICROSPHERES AS A DELIVERY SYSTEM FOR THE STUDY OF REPARATIVE DENTINOGENESIS, Endodontics & dental traumatology, 14(4), 1998, pp. 159-162
The characterization of poly(ethylene) glycol calcium citrate microsph
eres is described. The calcium content and content uniformity of micro
spheres, prepared at five concentrations ranging from 46.56 mu g/g to
81.49 mg/g, were determined by spectroscopy. Under sink conditions fir
st-order in vitro dissolution kinetics were observed. Granules contain
ing approximately SO mg Ca++/g PEG gave an in vitro calcium release ov
er a 3-day period similar to that of a calcium hydroxide product, Pulp
dent(R).