the cytotoxicity of there resin-based root canal sealers (AH26, AH-Plu
s, Topseal) was evaluated in vitro. The experiments included two cell
lines, L929 mouse skin fibroblasts and RPC-C2A rat pulp cells. The cyt
otoxicity was assessed by sulforodamine B (SRB) colorimetric assay and
hemocytometer viable cell counting after 24- and 48-h exposure. AH26
had a severe cytotoxic effect whilst Topseal and AH-Plus showed a mark
edly lower toxic influence on the cells during the experimental period
.