S. Lindskog et al., CHLORHEXIDINE AS A ROOT-CANAL MEDICAMENT FOR TREATING INFLAMMATORY LESIONS IN THE PERIODONTAL SPACE, Endodontics & dental traumatology, 14(4), 1998, pp. 186-190
The purpose of the present study was to investigate the therapeutic ef
fect of intra-canal application of chlorhexidine on inflammatory; root
resorption. Dental pulps from monkey incisors were infected and resea
led prior to extraction of the teeth. Root dentin was mechanically exp
osed and the teeth were replanted under aseptic conditions. After 4 we
eks, the experimental teeth were dressed with chlorhexidine gel and re
sealed. Animals were sacrificed 4 weeks later, and their jaws prepared
for histologic examination. Results showed that both marginal and api
cal periodontal inflammation and resorption were reduced in the chlorh
exidine-treated teeth. It was concluded that the use of intracanal chl
orhexidine may be a useful adjunct in the treatment of inflammatory ro
ot resorption, but further human trials need to be undertaken before i
ts clinical use call be recommended.