CHLORHEXIDINE AS A ROOT-CANAL MEDICAMENT FOR TREATING INFLAMMATORY LESIONS IN THE PERIODONTAL SPACE

The purpose of the present study was to investigate the therapeutic ef fect of intra-canal application of chlorhexidine on inflammatory; root resorption. Dental pulps from monkey incisors were infected and resea led prior to extraction of the teeth. Root dentin was mechanically exp osed and the teeth were replanted under aseptic conditions. After 4 we eks, the experimental teeth were dressed with chlorhexidine gel and re sealed. Animals were sacrificed 4 weeks later, and their jaws prepared for histologic examination. Results showed that both marginal and api cal periodontal inflammation and resorption were reduced in the chlorh exidine-treated teeth. It was concluded that the use of intracanal chl orhexidine may be a useful adjunct in the treatment of inflammatory ro ot resorption, but further human trials need to be undertaken before i ts clinical use call be recommended.