MATRIX-ASSISTED LASER-DESORPTION CHEMICAL-IONIZATION WITH REAGENT IONGENERATION DIRECTLY FROM A LIQUID MATRIX

Authors
BREUKER K KNOCHENMUSS R ZENOBI R
Citation
K. Breuker et al., MATRIX-ASSISTED LASER-DESORPTION CHEMICAL-IONIZATION WITH REAGENT IONGENERATION DIRECTLY FROM A LIQUID MATRIX, International journal of mass spectrometry and ion processes, 176(1-2), 1998, pp. 149-159
Citations number
31
Categorie Soggetti
Spectroscopy,"Physics, Atomic, Molecular & Chemical
Journal title
International journal of mass spectrometry and ion processes → ACNP
ISSN journal
13873806
Volume
176
Issue
1-2
Year of publication
1998
Pages
149 - 159
Database
ISI
SICI code
1387-3806(1998)176:1-2<149:MLCWRI>2.0.ZU;2-L
Abstract
Highly concentrated aqueous salt solutions were tested for their abili ty to serve as a reagent anion source for matrix-assisted laser desorp tion/chemical ionization (MALD/Cl). It was found that tetrabutylammoni um salt/silicon binary matrices yielded abundant deprotonated analyte signals. Moreover, controlled, specific fragmentation of carbohydrates , nucleotides, and peptides was observed, providing useful structural information. The degree of fragmentation was found to depend on the pr oton affinity of the reagent anion used. (Int J Mass Spectrom 176 (199 8) 149-159) (C) 1998 Elsevier Science B.V.