Aims: To assess trabecular density and structures at various cancellou
s bone sites in the foot using MR imaging. To compare the MRI findings
with the bone mineral density (BMD) values obtained by quantitative c
omputed tomography (QCT) in the lumbar vertebrae. Materials and Method
s: Bone mineral densities were measured by QCT in lumbar vertebrae 1 t
o 3 in ten patients with suspected osteoporosis. Sagittal images of th
e feet were obtained from these patients and also from seven healthy v
olunteers applying spin-echo and gradient-echo MR techniques. Results:
MR imaging revealed differences between patients with osteoporosis an
d individuals with healthy bones. Comparison of MR and BMD data reveal
ed a significant dependence of MR data on the bone density measured by
QCT (alpha < 0.05). In addition, a good correlation (r = 0.73) was fo
und between the results of the different MRI techniques. Conclusions:
The MR imaging techniques investigated offer an interesting tool for t
he non-invasive assessment of bony structures, at least at peripheral
locations with yellow bone marrow. To enable reliable application in t
he clinical routine setting, additional studies are required to identi
fy suitable standardized methods and establish normal ranges.