SYNTHESIS OF HETERODISACCHARIDE-CONTAINING PEPTIDES, FRAGMENTS OF ACTINOIDIN ANTIBIOTICS

Authors
MOUTON C TILLEQUIN F SEGUIN E MONNERET C
Citation
C. Mouton et al., SYNTHESIS OF HETERODISACCHARIDE-CONTAINING PEPTIDES, FRAGMENTS OF ACTINOIDIN ANTIBIOTICS, Journal of the Chemical Society. Perkin transactions. I (Print), (13), 1998, pp. 2055-2060
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I (Print) → ACNP
ISSN journal
0300922X
Issue
13
Year of publication
1998
Pages
2055 - 2060
Database
ISI
SICI code
0300-922X(1998):13<2055:SOHPFO>2.0.ZU;2-H
Abstract
Prototypes corresponding to glycopeptide fragments of actinoidin antib iotics have been synthesized using an L-acosaminyl-D-glucose-containin g heterodisaccharide linked to 4-hydroxyphenylglycine as pivotal synth on. This latter compound has been obtained by coupling of a suitably p rotected D-glucopyranosyl bromide with the blocked amino acid, followe d by selective deprotection of the glucopyranosyl moiety at C-2 and su bsequent stereospecific attachment of the acosaminyl unit.