Fructan is a general term used for any carbohydrate in which one or mo
re fructosyl-fructose link constitutes the majority of osidic bonds. T
his review focuses on the fate of inulin-type fructans (namely native
chicory inulin, oligofructose produced by the partial enzymatic hydrol
ysis of chicory inulin, and synthetic fructans produced by enzymatic s
ynthesis from sucrose) in the gastrointestinal tract, as well as on th
eir systemic physiological effects on mineral absorption, carbohydrate
and lipid metabolism, hormone balance, and nitrogen homeostasis. The
scientific evidence for the functional claims of inulin-type fructans
is discussed, as well as their potential application in risk reduction
of disease, namely constipation, infectious diarrhea, cancer, osteopo
rosis, atherosclerotic cardiovascular disease, obesity, and non-insuli
n dependent diabetes.