Background Latanoprost represents a new therapeutic option in the trea
tment of chronic open angle glaucoma. It has only recently been report
ed for the first time that latanoprost caused cystoid macular edema in
pseudophakic patients. Case report A 60-year-old pseudophakic patient
who suffered from a 10-year history of glaucoma, revealed a cystoid m
acular edema on fluorescence angiography after 10 days of treatment wi
th latanoprost. One week after cessation of latanoprost therapy the cy
stoid edema in fluorescence angiography had resolved and the vision im
proved from 0.4 to 0.8. Conclusions With respect to this severe compli
cation, latanoprost should be used with great care and in clear indica
tions, particularly in patients with risk of blood-aqueous leakage e.g
. pseudophakic patients.