A review of the structure-function relationships in normal, diseased a
nd reconstructed middle ears is presented. Variables used to describe
the system are sound pressure, volume velocity and acoustic impedance.
We discuss the following: (1) Sound can be transmitted from the ear c
anal to the cochlea via two mechanisms: the tympano-ossicular system (
ossicular coupling) and direct acoustic stimulation of the oval and ro
und windows (acoustic coupling). In the normal ear, middle-ear pressur
e gain, which is the result of ossicular coupling, is frequency-depend
ent and smaller than generally believed. Acoustic coupling is negligib
ly small in normal ears, but can play a significant role in some disea
sed and reconstructed ears. (2) The severity of conductive hearing los
s due to middle-ear disease or after tympanoplasty surgery can be pred
icted by the degree to which ossicular coupling, acoustic coupling, an
d stapes-cochlear input impedance are compromised. Such analyses are u
sed to explain the air-bone gaps associated with lesions such as ossic
ular interruption, ossicular fixation and tympanic membrane perforatio
n. (3) With type IV and V tympanoplasty, hearing is determined solely
by acoustic coupling. A quantitative analysis of structure-function re
lationships can both explain the wide range of observed postoperative
hearing results and suggest surgical guidelines in order to optimize t
he post-operative results. (4) In tympanoplasty types I, II and III, t
he hearing result depends on the efficacy of the reconstructed tympani
c membrane, the efficacy of the reconstructed ossicular chain and adeq
uacy of middle-ear aeration. Currently, our knowledge of the mechanics
of these three factors is incomplete. The mechanics of mastoidectomy
and stapedectomy are also discussed.