J. Finsterer et al., MALNUTRITION-INDUCED HYPOKALEMIC MYOPATHY IN CHRONIC-ALCOHOLISM, Journal of toxicology. Clinical toxicology, 36(4), 1998, pp. 369-373
Case Report: A 42-year-old man with a history of Billroth II-gastrecto
my, chronic alcoholism, and malnutrition developed acute tetraparesis,
two days before admission. He presented with bilateral, proximal uppe
r and lower limb weakness, Limb girdle wasting, bilaterally reduced Ac
hilles tendon reflexes, and bilateral stocking-type sensory disturbanc
es. Laboratory data revealed hypokalemia (2.2 mmol/L), elevated creati
ne kinase (7282 U/L), metabolic alkalosis and reduced urine potassium,
albumin, and total protein. Muscle biopsy showed atrophic, necrotic,
and regenerating fibers, endomysial macrophages, and vacuolar degenera
tion, interpreted as hypokalemic myopathy. With the correction of the
serum potassium, tetraparesis rapidly resolved. With other causes excl
uded, malnutrition and gastrectomy were considered responsible for hyp
okalemia in this patient with acute tetraparesis and chronic alcoholis
m.