MALNUTRITION-INDUCED HYPOKALEMIC MYOPATHY IN CHRONIC-ALCOHOLISM

Citation
J. Finsterer et al., MALNUTRITION-INDUCED HYPOKALEMIC MYOPATHY IN CHRONIC-ALCOHOLISM, Journal of toxicology. Clinical toxicology, 36(4), 1998, pp. 369-373
Citations number
10
Categorie Soggetti
Toxicology
ISSN journal
07313810
Volume
36
Issue
4
Year of publication
1998
Pages
369 - 373
Database
ISI
SICI code
0731-3810(1998)36:4<369:MHMIC>2.0.ZU;2-O
Abstract
Case Report: A 42-year-old man with a history of Billroth II-gastrecto my, chronic alcoholism, and malnutrition developed acute tetraparesis, two days before admission. He presented with bilateral, proximal uppe r and lower limb weakness, Limb girdle wasting, bilaterally reduced Ac hilles tendon reflexes, and bilateral stocking-type sensory disturbanc es. Laboratory data revealed hypokalemia (2.2 mmol/L), elevated creati ne kinase (7282 U/L), metabolic alkalosis and reduced urine potassium, albumin, and total protein. Muscle biopsy showed atrophic, necrotic, and regenerating fibers, endomysial macrophages, and vacuolar degenera tion, interpreted as hypokalemic myopathy. With the correction of the serum potassium, tetraparesis rapidly resolved. With other causes excl uded, malnutrition and gastrectomy were considered responsible for hyp okalemia in this patient with acute tetraparesis and chronic alcoholis m.