Endoscopic ultrasonography (EUS) is nowadays a clinically relevant tec
hnology and its findings can have a major impact on patient management
. This technique is currently indicated for staging digestive cancers,
assessment of submucosal tumors, diagnosis of intestinal wall infiltr
ative diseases, common bile-duct stones and gut neuroendocrine tumors.
As far as neoplasms are concerned, EUS appears to be a reliable and s
afe technique, thus making the physician able to plan either an aggres
sive surgical treatment, or a conservative palliative therapy. This is
of the utmost importance in order to optimize medical-related costs,
and to make the best therapeutic decision for each individual patient.
EUS is also helpful in monitoring the course of a disease, as it is s
imple and virtually without complications. When EUS findings are not s
ufficient for a complete diagnosis, it is now possible to perform an E
US-guided fine-needle biopsy, which can allow a cytological diagnosis.
Finally, some therapeutic endosonography-guided procedures are being
increasingly adopted, such as cystoenterostomy, celiac plexus neurolys
is, cholangio-pancreatography and selective injection of botulinum tox
in in the muscle layer of the lower esophageal sphincter.