BACKGROUND. The use of autologous fat has been advocated for tissue au
gmentation for over a century. However, this technique remains controv
ersial and many investigators have made suggestions to increase its po
tential. OBJECTIVES. TO develop a less traumatic method to collect, pu
rify, and reinject fat to obtain more dramatic augmentations for the c
osmetic improvement of contours and tissue defects. METHODS. Fat was c
ollected from the donor site following tumescent infiltration of tissu
e. A ''vented'' syringe with an atraumatic Mercedes tip was used to co
llect the fat and, after washing with lactated Ringers or saline, the
fat was transferred to small syringes for controlled injections. Small
filaments of fat were placed in multi-layers throughout the area of t
he defect or area of desired contour change. The unused fat was frozen
for a second or third injection session. RESULTS. The fat transfer me
thod yielded augmentations of 40%-120% of injected volume in the 339 a
reas treated. After 45-60 days, the implant was stabilized and remaine
d for the length of our study (up to 10 years). In several cases exces
sive fat had toe removed. ther than slight bruising, occasional divots
at the donor site, and three cases of bacterial infection, the autolo
gous tissue transfer was an uncomplicated event. CONCLUSION. Fat graft
ing has proven to be a safe and effective procedure for correcting and
enhancing tissue defects and contour deficiencies. (C) 1998 by the Am
erican Society for Dermatologic Surgery, Inc. Dermatol Surg 1998;24:85
7-865.