Progress in surface science and in computer methods has resulted in a
change from bench-scale laboratory tests to fundamental studies and la
rge scale pilot operation. Examples are given on the use of in-situ me
thods coupled to scale-up to pilot units. Catalysis may play a major r
ole in solving future problems in converting fossil fuels in a way bei
ng more efficient and environmentally acceptable. Examples are given f
or gas conversion comparing direct and indirect conversion routes, and
it is illustrated how coal based power plants may apply catalyst tech
nology. A positive attitude to long-term research is required to meet
these challenges to catalysis.