Angiomyolipoma is a benign mesenchymal tumor that has been reported fr
equently in the kidney but rarely in the liver. In the present study,
we present four cases of hepatic angiomyolipoma with different radiolo
gic appearances, discuss differential diagnosis, and review previously
reported cases. One of our cases was followed for 8 years. Computed t
omography (plain, enhanced, and dynamic study), magnetic resonance ima
ging (T1-weighted spin echo, T2-weighted spin echo, and dynamic study)
, ultrasonography, and angiography were performed in all cases. Althou
gh different radiologic appearances were observed in the tumors, based
on different proportions of fat, blood vessels, and muscle, three cas
es were diagnosed as angiomyolipoma. In one case, it was quite difficu
lt to make radiologic diagnosis; hepatocellular carcinoma with fatty m
etamorphosis in part was most likely suspected, but histopathological
examination revealed angiomyolipoma with few fat elements. In the pres
ent study, early and prolonged enhancement of the lesion with the spec
ial pattern of time density/intensity curve was significant for angiom
yolipoma, and we suggest that preoperative radiologic diagnosis of the
lesion is possible in most of the cases. However, it can be quite dif
ficult to distinguish angiomyolipoma from some hepatocellular carcinom
as with fatty metamorphosis.