Md. Rush et al., SKIN NECROSIS AND VENOUS THROMBOSIS FROM SUBCUTANEOUS INJECTION OF CHARCOAL LIGHTER FLUID (NAPTHA), The American journal of emergency medicine, 16(5), 1998, pp. 508-511
A 33 year-old white man injected approximately 4 cc of charcoal lighte
r fluid (99.4% naptha/0.6% inert ingredients) subcutaneously into his
left antecubital fossa. The injection resulted in the toxic necrosis o
f his volar forearm skin extending proximally to mid-humerus and dista
lly to the metacarpophalangeal joints of the left hand dorsally over a
6-day period. The patient ultimately required extensive surgical debr
idement, secondary operative closure, and approximately 150 cm(2) of s
plit-thickness skin grafting. This case demonstrates the potential for
widespread, delayed toxic necrosis of the skin resulting from subcuta
neous injection of naptha. This patient's case appears to represent th
e most severe and widespread case of toxic necrosis of the skin result
ing from the subcutaneous injection of hydrocarbons reported in the li
terature. This case also demonstrates extensive toxic thrombophlebitis
not reported in prior cases involving subcutaneous injection of hydro
carbons. Copyright (C) 1998 by W.B. Saunders Company.