HUMAN MALFORMATIONS SIMILAR TO THOSE IN THE MOUSE MUTATION DISORGANIZATION (DS)

Authors
ROBIN NH ADEWALE OO MCDONALDMCGINN D NADEAU JH ZACKAI EH BUCAN M
Citation
Nh. Robin et al., HUMAN MALFORMATIONS SIMILAR TO THOSE IN THE MOUSE MUTATION DISORGANIZATION (DS), Human genetics, 92(5), 1993, pp. 461-464
Citations number
20
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
92
Issue
5
Year of publication
1993
Pages
461 - 464
Database
ISI
SICI code
0340-6717(1993)92:5<461:HMSTTI>2.0.ZU;2-3
Abstract
We report two patients with malformations similar to those seen in mic e with the disorganization (Ds) mutation. The first case has a body wa ll defect, limb malformation, and hamartoma, while the second case has a partially duplicated foot, in addition to the other anomalies. We d iscuss the implications that recent advances regarding the genetic ana lysis of the mouse Ds locus have for the search for the human homologu e.