Indirect evidence suggests that cancer anorexia is associated with spe
cific aversions to macronutrients. To investigate this, patients with
cancer anorexia and hospitalized control subjects devised 3-day menus
comprising foods that they wished to eat. These foods were then provid
ed for 3 days and the intakes of each food carefully measured. As expe
cted, patients with cancer anorexia consumed substantially less energy
than hospitalized control subjects (6.0 +/- 0.9 MJ vs 9.5 +/- 0.5 MJ,
P < 0.001), However, macronutrient composition was consistently maint
ained in the patients with cancer anorexia. These data argue against c
ancer anorexia representing a state of macronutrient aversion.