Object. An aneurysm arising from the anterior wall of the internal car
otid artery (ICA) is a poorly understood entity. A small hemispherical
bulge from the anterior wall of the ICA, which is called a ''blood bl
isterlike aneurysm'' (BBA), may be confused with a tiny berry aneurysm
although the clinical features are distinctly different. This paper s
ummarizes the clinical course of patients with this lesion to clarify
the nature of the BBA. Methods. Six patients with BBAs who presented w
ith subarachnoid hemorrhage (SAH) are described. In all patients, the
initial angiogram obtained soon after SAH showed only a small bulge fr
om the anterior wall of the ICA. In three of the six patients this bul
ge had progressed to a saccular appearance within a few weeks. The wal
l of the lesion was so thin and fragile that the aneurysm ruptured at
the base during clipping or within a few hours after clipping in two p
atients. Conclusions. From the authors' experience, as well as a revie
w of the literature, which includes an autopsy study of similar cases,
it is inferred that these lesions are focal wall defects covered only
with thin fibrous tissue and that they are therefore not true aneurys
ms. Direct clipping often causes laceration of the lesion, whereas com
plete wrapping or clipping after wrapping is effective, but may fail t
o prevent growth of the aneurysm. Endovascular occlusion of the cervic
al ICA with or without bypass surgery, which is less risky than direct
surgery, is another option.