Mv. Glazkov et Ya. Meshcheryakova, EUKARYOTIC DNA TOPOISOMERASE AND IN-VITRO RECOMBINATION BETWEEN CIRCULAR SUPERCOILED PLASMID DNAS, Genetika, 34(7), 1998, pp. 1017-1020
Eukaryotic DNA topoisomerase II was shown to catalyze recombination be
tween circular supercoiled plasmid DNAs in vitro. The results obtained
are discussed with regard to the organization of eukaryotic chromosom
es in the form of topologically independent domains (loops).