TESTICULAR GERM-CELL TUMORS - MOLECULAR UNDERSTANDING AND CLINICAL IMPLICATIONS

Authors
LUTZKER SG BARNARD NJ
Citation
Sg. Lutzker et Nj. Barnard, TESTICULAR GERM-CELL TUMORS - MOLECULAR UNDERSTANDING AND CLINICAL IMPLICATIONS, Molecular medicine today, 4(9), 1998, pp. 404-411
Citations number
50
Categorie Soggetti
Medicine, Research & Experimental",Biology,"Cell Biology
Journal title
Molecular medicine today → ACNP
ISSN journal
13574310
Volume
4
Issue
9
Year of publication
1998
Pages
404 - 411
Database
ISI
SICI code
1357-4310(1998)4:9<404:TGT-MU>2.0.ZU;2-1
Abstract
It was recognized in the 1960s that testicular germ cell tumors were c urable with chemotherapeutic drugs, Since that time, newer drugs inclu ding cisplatin have increased the cure rate of these tumors to over 80 %, even in patients with metastatic disease. Germ cell tumors also exh ibit a unique biology and genetics that distinguish them from other so lid tumors and might contribute to their routine curability.