This review focuses on the genes for the enzymes 5-enolpyruvyl-3-phosp
hoshikimic acid synthase (EPSPS) and the glyphosate oxidoreductase (GO
X), These genes have been used to genetically engineer plants that are
resistant to the herbicide glyphosate, Overproduction of glyphosate-i
nsensitive EPSPS in transgenic crops has been used to overcome the:del
eterious effects of this herbicide. The introduction into plants of GO
X also Confers glyphosate tolerance to plants and augments the toleran
ce of transgenic plants already expressing a glyphosate tolerant EPSPS
. These genes also provide a method for selecting transformed plant ti
ssue using the glyphosate tolerance as the selectable marker in the pr
esence of inhibitory concentrations of glyphosate. Glyphosate tolerant
transgenic plants of beet, corn, cotton, lettuce, poplar, potato, rap
eseed, soybean, tobacco, tomato, end wheat have already been field tes
ted and are entering agriculture.