A new bis-norclerodane-type and two new clerodane-type diterpenoids we
re isolated from the Japanese liverwort, Jungermannia infusca, togethe
r with twelve known clerodane-, labdane- and ent-kaurane-type diterpen
oids. These structures were determined by the use of NMR spectroscopic
techniques, chemical degradation and X-ray crystallographic analyses.
The presence of(+)- and (-)-isoabienol were confirmed by chiral HPLC
analysis. (C) 1998 Elsevier Science Ltd. All rights reserved.