Dm. Bailey et al., IMPLICATIONS OF MODERATE ALTITUDE TRAINING FOR SEA-LEVEL ENDURANCE INELITE DISTANCE RUNNERS, European journal of applied physiology and occupational physiology, 78(4), 1998, pp. 360-368
Elite distance runners participated in one of two studies designed to
investigate the effects of moderate altitude training (inspiratory par
tial pressure of oxygen approximate to 115-125 mmHg) on submaximal, ma
ximal and supramaximal exercise performance following return to sea-le
vel. Study 1 (New Mexico, USA) involved 14 subjects who were assigned
to a 4-week altitude training camp (1500-2000m) whilst 9 performance-m
atched subjects continued with an identical training programme at sea-
level (CON). Ten EXP subjects who trained at 1640 m and 19 CON subject
s also participated in study 2 (Krugersdorp, South Africa). Selected m
etabolic and cardiorespiratory parameters were determined with the sub
jects at rest and during exercise 21 days prior to (PRE) and 10 and 20
days following their return to sealevel (POST). Whole blood lactate d
ecreased by 23% (P < 0.05 vs PRE) during submaximal exercise in the EX
P group only after 20 days at sea-level (study 1). However, the lactat
e threshold and other measures of running economy remained unchanged.
Similarly, supramaximal performance during a standardised track sessio
n did not change. Study 2 demonstrated that hypoxia per se did not alt
er performance. In contrast, in the EXP group supramaximal running vel
ocity decreased by 2% (P < 0.05) after 20 days at sea-level. Both stud
ies were characterised by a 50% increase in the frequency of upper res
piratory and gastrointestinal tract infections during the altitude soj
ourns, and two male subjects were diagnosed with infectious mononucleo
sis following their return to sea-level (study 1). Group mean plasma g
lutamine concentrations at rest decreased by 19% or 143 (74) mu M (P <
0.001) after 3 weeks at altitude, which may have been implicated in t
he increased incidence of infectious illness.