In 10 % of the cases, acute biliary pancratitis is severe, when system
ic complications occur during the first week and/or when local complic
ations start with the second week. Magnitude of pancreatic damage is n
ot related with the persistence of choledocolithiasis. Severe acute bi
liary pancreatitis is impaired by early biliary surgery, but surgery d
oes not increase mortality and morbidity in moderate acute biliary pan
creatitis. Endoscopic retrograde cholangio-pancreatography followed, w
hen necessary, by endoscopic sphincterotomy is not recommended in mode
rate acute pancreatitis. In severe acute biliary pancreatitis, prognos
is is not improved by endoscopic procedures. However, in case of acute
cholangitis, urgent endoscopic therapy is recommended.