K. Shiraki et al., LONG-TERM FOLLOW-UP OF SEVERE CENTRAL SEROUS CHORIORETINOPATHY USING INDOCYANINE GREEN ANGIOGRAPHY - LONG-TERM FOLLOW-UP OF CSC USING ICG ANGIOGRAPHY, International ophtalmology, 21(5), 1998, pp. 245-253
Background: The severe types of central serous chorioretinopathy (CSC)
have a chronic nature, suggesting that a pathological process persist
s subclinically. Indocyanine green (ICG) angiography recently revealed
intrachoroidal dye leakage and its static nature in CSC. As the intra
choroidal dye leakage was suspected to be relevant to the disease proc
ess, the long-term persistence of intrachoroidal ICG leakage was exami
ned in four patients of the severe types of CSC. Methods: ICG angiogra
phy was performed periodically over more than three years in three pat
ients and two years in one patient. One patient had CSC with bullous r
etinal detachment, and the other three had chronic CSC or diffuse reti
nal pigment epitheliopathy. Results: Intrachoroidal ICG leakage persis
ted in all the patients. However, a change in location of persistent i
ntrachoroidal leakage or disappearance of intrachoroidal leakage regar
dless of no progression of retinal pigment epithelial alteration was n
oted in one eye of two patients. Conclusions: Pathology causing intrac
horoidal ICG leakage persisted subclinically for a long period. Howeve
r, location and extent of the intrachoroidal leakage could change duri
ng a long-term follow-up period.